Nobel prize: How cells sense oxygen

Nobel prize: How cells sense oxygen

Nobel Prize 2019: Three scientists who discovered how cells sense and adapt to oxygen levels.

Sir Peter Ratcliffe, of the University of Oxford and Francis Crick Institute, William Kaelin, of Harvard, and Gregg Semenza, of Johns Hopkins University share the physiology or medicine prize.

Their work is leading to new treatments for anaemia and even cancer.

The role of oxygen-sensing is also being investigated in diseases from heart failure to chronic lung disease.
The Swedish Academy, which awards the prize, said: “The fundamental importance of oxygen has been understood for centuries, but how cells adapt to changes in levels of oxygen has long been unknown.”

Oxygen levels vary in the body, particularly:

  • during exercise
  • at high altitude
  • after a wound disrupts the blood supply

And when they drop, cells rapidly have to adapt their metabolism.

Why does this matter? The oxygen-sensing ability of the body has a role in the immune system and the earliest stages of development inside the womb.

If oxygen levels are low, it can trigger the production of red blood cells or the construction of blood vessels to remedy this.

More red blood cells mean the body is able to carry more oxygen and is why athletes train at altitude.

So, drugs that mimic it may be an effective treatment for anaemia. Full STory

 

‘Sex for grades’: Undercover in West African universities

Academic institutions in West Africa have increasingly been facing allegations of sexual harassment by lecturers. This type of abuse is said to be endemic, but it’s almost never proven.

After gathering dozens of testimonies, BBC Africa Eye sent undercover journalists posing as students inside the University of Lagos and the University of Ghana. Full Story

 

What Japan can teach us about cleanliness?

The students sit with their satchels on their desks, eager to get home after another long day of seven 50-minute classes. They listen patiently as their teacher makes a few announcements about tomorrow’s timetable. Then, as every day, the teacher’s final words: “OK everybody, today’s cleaning roster. Lines one and two will clean the classroom. Lines three and four, the corridor and stairs. And line five will clean the toilets.” Full Story

Other Articles of Interest

The Permabear Doomster's Paradox

The Permabear Doomster’s Paradox: Blending Prudence with Market Savvy

Navigating the Abyss: The Permabear Doomster’s Creed In the shadowy realms of market analysis, there lurks a breed of thinkers ...
Stock Market Manipulation

Illuminating the Shadows of Stock Market Manipulation

Navigating the Pitfalls of Stock Market Manipulation: A Treatise for the Discerning Investor In finance, where fortunes are forged and ...
Perception Manipulation in Trading: Cutting Through the Psychological Fog

Perception Manipulation in Trading: Cutting Through the Psychological Fog

Revitalizing Investment Insights: The Power of Perception In the ever-evolving landscape of investment, perception is not just a buzzword; it’s ...
contrarianism definition

Embracing Contrarianism: The Path to Innovative Thinking

In an era where information overflows, and opinions are a dime a dozen, the contrarian stance stands out as a ...
reasons why ai is bad

Unmasking the Dark Side of Artificial Intelligence

Artificial Intelligence (AI) is undeniably transforming the world as we know it. AI is becoming an integral part of our ...
Banksters Band: Exploiting the Disadvantaged

Banksters Band: Exploiting the Disadvantaged

Banksters Band: Exploiting the Disadvantaged, Fostering the Wealth of the Privileged The role of the Federal Reserve in economic stabilisation ...
Who Makes Blue Gas

The Power Producers: Discovering Who Makes Blue Gas?

What is blue gas, and who makes it? Blue hydrogen, often referred to as blue gas, has become a focal ...
investment pyramid

Investment Pyramid: A Chic Strategy in the Modern Investment Era

An investment pyramid, or risk pyramid, functions as a tactical roadmap for portfolio distribution, considering the varying risk levels tied ...

(no title)

[xyz-ips snippet=”STOCK”] ...

MU Table pdf preview

[dearpdf id=”1209″][/dearpdf] ...